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- 商品货号：G106379
- accession：NM_133509
- 基因别名：RAD51B
- 基因描述：Homo sapiens RAD51 paralog B (RAD51B), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1155
- 翻译后氨基酸长度：384
- TranscriptVariant：This variant (3) represents the longest transcript. It encodes the isoform (3) that has a distinct C-terminus, compared to isoform 1 and 2.
- 基因简介：The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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