服务热线：
- 商品货号：G106345
- accession：NM_001946
- 基因别名：DUSP6
- 基因描述：Homo sapiens dual specificity phosphatase 6 (DUSP6), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：1146
- 翻译后氨基酸长度：381
- TranscriptVariant：This variant (1) represents the full-length transcript (containing exon 2) and encodes the longer isoform (a).
- 基因简介：The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
服务时间：24小时在线客服
客服热线：400-000-7085
丰晖生物
中国优质生物资源平台
在线客服