- accession:NM_001286827
- 基因别名:GABRA2
- 基因描述:Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:1371
- 翻译后氨基酸长度:456
- TranscriptVariant:This variant (3) lacks an alternate exon in the 5' end and contains an alternate in-frame exon in the 3' end, which leads to the use of a downstream start codon compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus and contains an alternate segment compared to isoform a.
- 基因简介:GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
- 规格:10ul 质粒
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