- accession:NM_001243723
- 基因别名:SETMAR
- 基因描述:Homo sapiens SET domain and mariner transposase fusion gene (SETMAR), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1638
- 翻译后氨基酸长度:545
- TranscriptVariant:This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- 基因简介:This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
- 规格:10ul 质粒
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