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人RAMP1(NM_005855)ORF克隆
人RAMP1(NM_005855)ORF克隆
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  • 商品货号:F103114
  • accession:NM_005855
  • 基因别名:RAMP1
  • 基因描述:Homo sapiens receptor (G protein-coupled) activity modifying protein 1 (RAMP1), mRNA.
  • 载体: pcDNA3.1-3xFlag
  • CDS区长度:447
  • 翻译后氨基酸长度:148
  • 基因简介:The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列