- accession:NM_000103
- 基因别名:CYP19A1
- 基因描述:Homo sapiens cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1512
- 翻译后氨基酸长度:503
- TranscriptVariant:This variant (1) does not include exon 2a, and thus has a shorter 5' UTR than transcript variant 2. Both variants encode the same protein.
- 基因简介:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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