- accession:NM_170738
- 基因别名:MRPL11
- 基因描述:Homo sapiens mitochondrial ribosomal protein L11 (MRPL11), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:501
- 翻译后氨基酸长度:166
- TranscriptVariant:This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, which results in an isoform (b) that lacks an internal segment of sequence, compared to isoform a.
- 基因简介:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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