- accession:NM_144489
- 基因别名:RGS3
- 基因描述:Homo sapiens regulator of G-protein signaling 3 (RGS3), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:936
- 翻译后氨基酸长度:311
- TranscriptVariant:This variant (5) lacks several 5' exons but includes an alternate 5' exon, and it thus differs in the 5' UTR, lacks a large portion of the 5' coding region, and uses an alternate start codon, compared to variant 6. The encoded isoform (5, also known as RGS3S in PubMed ID:12036301) has a significantly shorter and distinct N-terminus, compared to isoform 6.
- 基因简介:This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]
- 规格:10ul 质粒
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