- accession:NM_000207
- 基因别名:INS
- 基因描述:Homo sapiens insulin (INS), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:333
- 翻译后氨基酸长度:110
- TranscriptVariant:This transcript (1) represents the shortest variant. Variants 1-3 encode the same protein.
- 基因简介:After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列