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- 商品货号：G104998
- accession：NM_013258
- 基因别名：PYCARD
- 基因描述：Homo sapiens PYD and CARD domain containing (PYCARD), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：588
- 翻译后氨基酸长度：195
- TranscriptVariant：This variant (1) represents the longer transcript and encodes the longer isoform (a).
- 基因简介：This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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