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- accession：NM_001012722
- 基因别名：RGR
- 基因描述：Homo sapiens retinal G protein coupled receptor (RGR), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：762
- 翻译后氨基酸长度：253
- TranscriptVariant：This variant (3) uses an alternate in-frame splice site in the 5' coding region and lacks an exon in the 3' coding region, compared to variant 1. The resulting protein (isoform 3) is shorter than isoform 1.
- 基因简介：This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
