- accession:NM_002894
- 基因别名:RBBP8
- 基因描述:Homo sapiens retinoblastoma binding protein 8 (RBBP8), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2694
- 翻译后氨基酸长度:897
- TranscriptVariant:This variant (1) represents the longest transcript. Variants 1 and 2 both encode isoform a.
- 基因简介:The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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