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人 ZFHX3 (NM_001164766) cDNA克隆
人 ZFHX3 (NM_001164766) cDNA克隆
  • 商品货号:FC106487
  • 已售 7 件 | 评价 0 人次 | 关注度 421
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    • accession:NM_001164766
    • 基因别名:ZFHX3
    • 基因描述:Homo sapiens zinc finger homeobox 3 (ZFHX3), transcript variant B, mRNA.
    • 载体:现货载体
    • CDS区长度:8370
    • 翻译后氨基酸长度:2789
    • TranscriptVariant:This variant (B) represents use of an alternate promoter and 5' UTR, lacks an alternate coding exon, and uses a downstream start codon, compared to variant A. The resulting isoform (B) has a shorter N-terminus, compared to isoform A.
    • 基因简介:This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列