- accession:NM_001143783
- 基因别名:FES
- 基因描述:Homo sapiens feline sarcoma oncogene (FES), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2295
- 翻译后氨基酸长度:764
- TranscriptVariant:This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1, and encodes a protein (isoform 2) with a shorter N-terminus, compared to isoform 1.
- 基因简介:This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]
- 规格:10ul 质粒
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