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人 FBXO18 (NM_178150) cDNA克隆
人 FBXO18 (NM_178150) cDNA克隆
  • 商品货号:FC106430
  • 已售 7 件 | 评价 0 人次 | 关注度 300
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    • accession:NM_178150
    • 基因别名:FBXO18
    • 基因描述:Homo sapiens F-box protein, helicase, 18 (FBXO18), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:3132
    • 翻译后氨基酸长度:1043
    • TranscriptVariant:This variant (2) differs at the 5' end compared to variant 1, resulting in translation initiation from an in-frame downstream AUG, and an isoform (2) with a shorter N-terminus compared to isoform 1.
    • 基因简介:This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列