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人 RBM14 (NM_001198836) cDNA克隆
人 RBM14 (NM_001198836) cDNA克隆
  • 商品货号:FC106271
  • 已售 7 件 | 评价 0 人次 | 关注度 332
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    • accession:NM_001198836
    • 基因别名:RBM14
    • 基因描述:Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:471
    • 翻译后氨基酸长度:156
    • TranscriptVariant:This variant (2) uses an alternate donor splice site at an internal coding exon compared to variant 1. This results in a frame-shift and an isoform (2, also known as CoAM or coactivator modulator) with a distinct and shorter C-terminus compared to isoform 1. This isoform lacks the TRBP-interacting domain, and functions as a transcriptional repressor by inhibiting the activity of isoform 1 (PMID:11443112).
    • 基因简介:This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列