- accession:NM_020327
- 基因别名:ACVR1B
- 基因描述:Homo sapiens activin A receptor, type IB (ACVR1B), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1362
- 翻译后氨基酸长度:453
- TranscriptVariant:This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform 1.
- 基因简介:This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
- 规格:10ul 质粒
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