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人 POLH (NM_006502) cDNA克隆
人 POLH (NM_006502) cDNA克隆
  • 商品货号:FC105951
  • 已售 7 件 | 评价 0 人次 | 关注度 261
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    • accession:NM_006502
    • 基因别名:POLH
    • 基因描述:Homo sapiens polymerase (DNA directed), eta (POLH), mRNA.
    • 载体:现货载体
    • CDS区长度:2142
    • 翻译后氨基酸长度:713
    • 基因简介:This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列