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- accession：NM_004811
- 基因别名：LPXN
- 基因描述：Homo sapiens leupaxin (LPXN), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1161
- 翻译后氨基酸长度：386
- TranscriptVariant：This variant (2) has a different first exon at the 5' end, compared to variant 1. This difference results in a unique 5' UTR and 5' coding region and an isoform (2) with a shorter N-terminus, compared to isoform 1.
- 基因简介：The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
