- accession:NM_001007273
- 基因别名:DUSP13
- 基因描述:Homo sapiens dual specificity phosphatase 13 (DUSP13), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:876
- 翻译后氨基酸长度:291
- TranscriptVariant:This variant (3) lacks several internal exons, compared to variant 1, resulting in a distinct protein (isoform 3, also called TMDP-L1), compared to isoform 1. Efforts to detect expression of isoform 3 were unsuccessful.
- 基因简介:Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列