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人 ITM2B (NM_021999) cDNA克隆
人 ITM2B (NM_021999) cDNA克隆
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  • 商品货号:G100931
  • accession:NM_021999
  • 基因别名:ITM2B
  • 基因描述:Homo sapiens integral membrane protein 2B (ITM2B), mRNA.
  • 载体:现货载体
  • CDS区长度:801
  • 翻译后氨基酸长度:266
  • 基因简介:Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列