- accession:NM_003836
- 基因别名:DLK1
- 基因描述:Homo sapiens delta-like 1 homolog (Drosophila) (DLK1), mRNA.
- 载体: 现货载体
- CDS区长度:1152
- 翻译后氨基酸长度:383
- 基因简介:This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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