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- accession：NM_006354
- 基因别名：TADA3
- 基因描述：Homo sapiens transcriptional adaptor 3 (TADA3), transcript variant 1, mRNA.
- 载体： 现货载体
- CDS区长度：1299
- 翻译后氨基酸长度：432
- TranscriptVariant：This variant (1) encodes the longer protein. Variants 1 and 3 encode the same isoform (a).
- 基因简介：DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
- 载体信息：自有图片地址
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
