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人PDHB(NM_000925)ORF克隆
人PDHB(NM_000925)ORF克隆
  • 商品货号:FO103394
  • 已售 31 件 | 评价 0 人次 | 关注度 657
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    • accession:NM_000925
    • 基因别名:PDHB
    • 基因描述:Homo sapiens pyruvate dehydrogenase (lipoamide) beta (PDHB), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:1080
    • 翻译后氨基酸长度:359
    • TranscriptVariant:This variant (1) represents the predominant transcript and encodes the longer isoform (1).
    • 基因简介:The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列