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人OGG1(NM_002542)ORF克隆
人OGG1(NM_002542)ORF克隆
  • 商品货号:FO103286
  • 已售 31 件 | 评价 0 人次 | 关注度 631
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    • accession:NM_002542
    • 基因别名:OGG1
    • 基因描述:Homo sapiens 8-oxoguanine DNA glycosylase (OGG1), transcript variant 1a, mRNA.
    • 载体: 现货载体
    • CDS区长度:1038
    • 翻译后氨基酸长度:345
    • TranscriptVariant:Transcript variant 1a represents the predominant form of this gene.
    • 基因简介:This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列