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人SNX15(NM_013306)ORF克隆
人SNX15(NM_013306)ORF克隆
  • 商品货号:FO103277
  • 已售 31 件 | 评价 0 人次 | 关注度 635
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    • accession:NM_013306
    • 基因别名:SNX15
    • 基因描述:Homo sapiens sorting nexin 15 (SNX15), transcript variant A, mRNA.
    • 载体: 现货载体
    • CDS区长度:1029
    • 翻译后氨基酸长度:342
    • TranscriptVariant:This variant (A, also known as SNX15) represents the longer transcript and encodes the longer isoform (A).
    • 基因简介:This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列