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- 靶点-Target: PHAPI2
- MW(Observed): 29kD
- 宿主物种-Host Species: Rabbit
- 同种型-Isotype: IgG
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 浓度: 1 mg/ml
- 克隆性: Polyclonal
- 免疫原: The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50
- 特异性: PHAPI2 Polyclonal Antibody detects endogenous levels of PHAPI2 protein.
- 基因名称: ANP32B
- 蛋白名称: Acidic leucine-rich nuclear phosphoprotein 32 family member B
- Organism-1: Human
- 基因ID-1: 10541
- SwissProt-1: Q92688
- Organism-2: Mouse
- 基因ID-2: 67628
- SwissProt-2: Q9EST5
- Organism-3: Rat
- 基因ID-3: 170724
- SwissProt-3: Q9EST6
- 背景: function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,
- 细胞定位: [Isoform 1]: Nucleus . Cytoplasm . Accumulates in the nuclei at the S phase. .; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.