• 靶点-Target： COX17
• MW(Observed)： 7kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： The antiserum was produced against synthesized peptide derived from human COX17. AA range:1-50
• 特异性： COX17 Polyclonal Antibody detects endogenous levels of COX17 protein.
• 基因名称： COX17
• 蛋白名称： Cytochrome c oxidase copper chaperone
• Organism-1： Human
• 基因ID-1： 10063
• SwissProt-1： Q14061
• Organism-2： Mouse
• 基因ID-2： 12856
• SwissProt-2： P56394
• 背景： Cytochrome c oxidase (COX)， the terminal component of the mitochondrial respiratory chain， catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer， and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit， but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provi
• 细胞定位： Mitochondrion intermembrane space . Cytoplasm .

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