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- 靶点-Target: DNM3A
- MW(Observed): 100kD
- 宿主物种-Host Species: Rabbit
- 同种型-Isotype: IgG
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-2000;ELISA 1:5000-20000
- 组成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 浓度: 1 mg/ml
- 克隆性: Polyclonal
- 免疫原: Synthesized peptide derived from human protein . at AA range: 10-90
- 特异性: DNM3A Polyclonal Antibody detects endogenous levels of protein.
- 基因名称: DNMT3A
- 蛋白名称: DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)
- Organism-1: Human
- 基因ID-1: 1788
- SwissProt-1: Q9Y6K1
- Organism-2: Mouse
- SwissProt-2: O88508
- Organism-3: Rat
- SwissProt-3: Q1LZ53
- 背景: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016],
- 细胞定位: Nucleus . Chromosome . Cytoplasm . Accumulates in the major satellite repeats at pericentric heterochromatin. .