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- 靶点-Target: eEF2
- MW(Calculated): 95kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:1000-1:2000;Not yet tested in other applications.
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: Affinity purification
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant human EF-2 protein fragments expressed in E.coli.
- 特异性: EF-2 Monoclonal Antibody detects endogenous levels of EF-2 protein.
- 基因名称: EEF2
- 蛋白名称: Elongation factor 2
- Organism-1: Human
- 基因ID-1: 1938
- SwissProt-1: P13639
- Organism-2: Mouse
- 基因ID-2: 13629
- SwissProt-2: P58252
- Organism-3: Rat
- 基因ID-3: 29565
- SwissProt-3: P05197
- 背景: This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008],
- 细胞定位: Cytoplasm . Nucleus . Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. .