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- 靶点-Target: Histone H3
- MW(Observed): 15-17kD
- 宿主物种-Host Species: Rabbit
- 同种型-Isotype: IgG
- 修饰-Modification: Tri Methyl
- 推荐稀释比: WB 1:500-1000
- 组成: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Polyclonal
- 免疫原: Synthetic Peptide of Histone H3 (Tri Methyl Lys79)
- 特异性: The antibody detects endogenous Histone H3 (Tri Methyl Lys79) protein.
- 基因名称: HIST1H3A/HIST1H3B/HIST1H3C/HIST1H3D/HIST1H3E/HIST1H3F/HIST1H3G/HIST1H3H/HIST1H3I/HIST1H3J/HIST2H3A/HIST2H3C/HIST2H3D/H3F3A/H3F3B
- 蛋白名称: Histone H3.1/Histone H3.2/Histone H3.3
- Organism-1: Human
- 基因ID-1: 8350;8351;8352;8353;8354;8355;8356;8357;8358;8968
- SwissProt-1: P68431;Q71DI3;P84243
- Organism-2: Mouse
- 基因ID-2: 319152;15077;15078
- Organism-3: Rat
- 基因ID-3: 291159;100361558
- SwissProt-3: Q6LED0;P84245
- 背景: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],
- 细胞定位: Nucleus. Chromosome.