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- 靶点-Target: PROC
- MW(Observed): 17kD,45kD
- 宿主物种-Host Species: Rabbit
- 同种型-Isotype: IgG
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 浓度: 1 mg/ml
- 克隆性: Polyclonal
- 免疫原: Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)
- 特异性: This antibody detects endogenous levels of Human PROC (light chain, Cleaved-Leu179, protein was cleaved amino acid sequence between 179-180 )
- 基因名称: PROC
- 蛋白名称: PROC (light chain, Cleaved-Leu179)
- Organism-1: Human
- 基因ID-1: 5624
- SwissProt-1: P04070
- Organism-2: Mouse
- 基因ID-2: 19123
- SwissProt-2: P33587
- Organism-3: Rat
- 基因ID-3: 25268
- SwissProt-3: P31394
- 背景: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],
- 细胞定位: Secreted . Golgi apparatus . Endoplasmic reticulum .