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- 靶点-Target: Plasminogen HC A
- MW(Observed): 54kD
- 宿主物种-Host Species: Rabbit
- 同种型-Isotype: IgG
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 浓度: 1 mg/ml
- 克隆性: Polyclonal
- 免疫原: The antiserum was produced against synthesized peptide derived from human PLMN. AA range:79-128
- 特异性: Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody detects endogenous levels of fragment of activated Plasminogen HC A short form protein resulting from cleavage adjacent to V98.
- 基因名称: PLG
- 蛋白名称: Plasminogen
- Organism-1: Human
- 基因ID-1: 5340
- SwissProt-1: P00747
- Organism-2: Mouse
- 基因ID-2: 18815
- SwissProt-2: P20918
- Organism-3: Rat
- 基因ID-3: 85253
- SwissProt-3: Q01177
- 背景: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],
- 细胞定位: Secreted . Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.