• 靶点-Target： KLK8
• MW(Observed)： 24kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： The antiserum was produced against synthesized peptide derived from human Neuropsin. AA range:14-63
• 特异性： Cleaved-KLK8 (V33) Polyclonal Antibody detects endogenous levels of fragment of activated KLK8 protein resulting from cleavage adjacent to V33.
• 基因名称： KLK8
• 蛋白名称： Kallikrein-8
• Organism-1： Human
• 基因ID-1： 11202
• SwissProt-1： O60259
• Organism-2： Mouse
• SwissProt-2： Q61955
• 背景： Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq， Jul 2013]，
• 细胞定位： Secreted . Cytoplasm . Shows a cytoplasmic distribution in the keratinocytes.

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