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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 人源 > 人 UTRN (NM_007124) cDNA克隆
人 UTRN (NM_007124) cDNA克隆
人 UTRN (NM_007124) cDNA克隆
  • 商品货号：FC165553
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    • accession：NM_007124
    • 基因别名：DRP; DMDL; DRP1
    • 基因描述：Homo sapiens utrophin (UTRN), mRNA.
    • 载体：现货载体
    • CDS区长度：10302
    • 翻译后氨基酸长度：3433
    • 基因简介：This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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