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人 NOTCH3 (NM_000435) cDNA克隆
人 NOTCH3 (NM_000435) cDNA克隆
¥6500元
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  • 商品货号:G169865
  • accession:NM_000435
  • 基因别名:IMF2; CASIL; CADASIL
  • 基因描述:Homo sapiens notch 3 (NOTCH3), mRNA.
  • 载体:现货载体
  • CDS区长度:6966
  • 翻译后氨基酸长度:2321
  • 基因简介:This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列