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人 LRBA (NM_001199282) cDNA克隆
人 LRBA (NM_001199282) cDNA克隆
  • 商品货号:FC170018
  • 已售 7 件 | 评价 0 人次 | 关注度 403
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    • accession:NM_001199282
    • 基因别名:BGL; LBA; CDC4L; CVID8; LAB300
    • 基因描述:Homo sapiens LPS-responsive vesicle trafficking, beach and anchor containing (LRBA), transcript variant 1, mRNA.
    • 载体:现货载体
    • CDS区长度:8556
    • 翻译后氨基酸长度:2851
    • TranscriptVariant:This variant (1) differs in the 5' UTR, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 2. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 2.
    • 基因简介:The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列