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人 CD163 (NM_203416) cDNA克隆
人 CD163 (NM_203416) cDNA克隆
  • 商品货号:FC169373
  • 已售 4 件 | 评价 0 人次 | 关注度 576
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    • accession:NM_203416
    • 基因别名:M130; MM130
    • 基因描述:Homo sapiens CD163 molecule (CD163), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:3366
    • 翻译后氨基酸长度:1121
    • TranscriptVariant:This variant (2), also known as short tail variant, uses an alternate acceptor splice site at the penultimate exon compared to variant 1. This results in a frame-shift, and an isoform (b) with a shorter and distinct C-terminus compared to isoform a.
    • 基因简介:The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列