×
![]()
- accession：NM_001240
- 基因别名：CCNT; CYCT1; HIVE1
- 基因描述：Homo sapiens cyclin T1 (CCNT1), transcript variant a, mRNA.
- 载体：现货载体
- CDS区长度：2181
- 翻译后氨基酸长度：726
- TranscriptVariant：This variant (a, also known as FL and CycT1a) represents the longer transcript and encodes the longer isoform (a).
- 基因简介：This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
