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- accession：NM_175931
- 基因别名：ETO2; MTG16; MTGR2; ZMYND4
- 基因描述：Homo sapiens core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (CBFA2T3), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1704
- 翻译后氨基酸长度：567
- TranscriptVariant：This variant (2) differs in the 5' UTR and lacks an alternate in-frame coding exon, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (2) that lacks an internal segment and has a shorter N-terminus, compared to isoform 1. Variant 2 is also known as MTG16b.
- 基因简介：This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
