- accession:NM_001142930
- 基因别名:AAC11; AAC-11
- 基因描述:Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1575
- 翻译后氨基酸长度:524
- TranscriptVariant:This variant (1) encodes the longest isoform (a).
- 基因简介:This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列