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人 ABCB11 (NM_003742) cDNA克隆
人 ABCB11 (NM_003742) cDNA克隆
  • 商品货号:FC168929
  • 已售 4 件 | 评价 0 人次 | 关注度 1170
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    • accession:NM_003742
    • 基因别名:BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2
    • 基因描述:Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ABCB11), mRNA.
    • 载体:现货载体
    • CDS区长度:3966
    • 翻译后氨基酸长度:1321
    • 基因简介:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列