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- accession：NM_001270570
- 基因描述：Rattus norvegicus histamine receptor H3 (Hrh3), transcript variant 8, mRNA.
- 载体：现货载体
- CDS区长度：1035
- 翻译后氨基酸长度：344
- TranscriptVariant：This variant (8) is alternatively spliced at the 3' end and uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1. The latter causes a frame-shift, and a shorter isoform (8) containing 6 transmembrane domains and missing part of the third intracellular loop compared to isoform H3A.
- 基因简介：This gene encodes a histamine H3 receptor that belongs to the superfamily of G-protein coupled receptors. This protein functions as a presynaptic autoreceptor on histamine neurons in the brain, and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. It is deemed a great target for the development of therapeutics for numerous disorders, including obesity, epilepsy, and such cognitive diseases as attention deficit hyperactivity disorder and Alzheimer's disease. Several alternatively spliced transcript variants encoding different isoforms, with different brain expression patterns and signaling properties, have been described for this gene. [provided by RefSeq, Jul 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
