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人IL12RB2(NM_001559)ORF克隆
人IL12RB2(NM_001559)ORF克隆
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  • 商品货号:F150029
  • accession:NM_001559
  • 基因别名:IL12RB2
  • 基因描述:Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2), transcript variant 1, mRNA.
  • 载体:现货载体
  • CDS区长度:2589
  • 翻译后氨基酸长度:862
  • TranscriptVariant:This variant (1) encodes the longest isoform (a).
  • 基因简介:The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列