- 商品货号:F150029
- accession:NM_001559
- 基因别名:IL12RB2
- 基因描述:Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2589
- 翻译后氨基酸长度:862
- TranscriptVariant:This variant (1) encodes the longest isoform (a).
- 基因简介:The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列