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人SIGLEC8(NM_014442)ORF克隆
人SIGLEC8(NM_014442)ORF克隆
¥1500元
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  • 商品货号:F145047
  • accession:NM_014442
  • 基因别名:SIGLEC8
  • 基因描述:Homo sapiens sialic acid binding Ig-like lectin 8 (SIGLEC8), mRNA.
  • 载体:现货载体
  • CDS区长度:1500
  • 翻译后氨基酸长度:499
  • 基因简介:Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列