- accession:NM_012144
- 基因别名:DNAI1
- 基因描述:Homo sapiens dynein, axonemal, intermediate chain 1 (DNAI1), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2100
- 翻译后氨基酸长度:699
- TranscriptVariant:This variant (1) encodes isoform 1.
- 基因简介:This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列