- accession:NM_000121
- 基因别名:EPOR
- 基因描述:Homo sapiens erythropoietin receptor (EPOR), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1527
- 翻译后氨基酸长度:508
- TranscriptVariant:This variant (1) encodes the functional protein.
- 基因简介:This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列