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人CRTC2(NM_181715)ORF克隆
人CRTC2(NM_181715)ORF克隆
¥2100元
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  • 商品货号:F135918
  • accession:NM_181715
  • 基因别名:CRTC2
  • 基因描述:Homo sapiens CREB regulated transcription coactivator 2 (CRTC2), mRNA.
  • 载体:现货载体
  • CDS区长度:2082
  • 翻译后氨基酸长度:693
  • 基因简介:This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列