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人DNM1(NM_001005336)ORF克隆
人DNM1(NM_001005336)ORF克隆
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  • 商品货号:F134112
  • accession:NM_001005336
  • 基因别名:DNM1
  • 基因描述:Homo sapiens dynamin 1 (DNM1), transcript variant 2, mRNA.
  • 载体:现货载体
  • CDS区长度:2556
  • 翻译后氨基酸长度:851
  • TranscriptVariant:This variant (2) includes an alternate exon in the 3' coding region that results in a frameshift and an early stop codon, compared to variant 1. The resulting isoform (2), also known as internal form 2 and the short C-terminal form, is shorter and has a distinct C-terminus, compared to isoform 1.
  • 基因简介:This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列