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人PTPN21(NM_007039)ORF克隆
人PTPN21(NM_007039)ORF克隆
  • 商品货号:FO129784
  • 已售 5 件 | 评价 0 人次 | 关注度 345
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    • accession:NM_007039
    • 基因别名:PTPN21
    • 基因描述:Homo sapiens protein tyrosine phosphatase, non-receptor type 21 (PTPN21), mRNA.
    • 载体: 现货载体
    • CDS区长度:3525
    • 翻译后氨基酸长度:1174
    • 基因简介:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列